Enterovirus 1177

Enterovirus-infeksjoner kan forårsake et vidt spektrum av sykdommer hos mennesker, hyppigst blant barn og spedbarn. Det kan være utslettsykdommer, hjernebetennelser, øyebetennelser, luftveisinfeksjoner eller betennelser i nervesystemet Enterovirus er en slekt av virus innenfor familien Picornaviridae og omfatter Coxsackievirus, ECHO-virus og poliovirus. Enterovirus er RNA-virus som vanligvis vokser i tarmen, men som kan spre seg til andre organer. Infeksjoner med enterovirus opptrer vanligvis uten at man merker det, men kan også gi alvorlig sykdom. Viruset smitter fra avføring via hender til mat (fekal-oral smittevei. Enteroviruses are actually a group of viruses, including EV-D68, that can cause cold-like symptoms, or other more serious infections. Here's what to know about enterovirus infections, according to.

Enterovirusinfeksjoner - NHI

  1. Enterovirus is a genus of positive-sense single-stranded RNA viruses associated with several human and mammalian diseases. Enteroviruses are named by their transmission-route through the intestine (enteric meaning intestinal). Serologic studies have distinguished 71 human enterovirus serotypes on the basis of antibody neutralization tests. . Additional antigenic variants have been defined.
  2. Enterovirus Real Time PCR. Analyseres ved. UNN, Avdeling for mikrobiologi og smittevern Molekylærbiologisk enhet (generell) telefon 776 69058. Dersom du ikke får svar kan du ringe mikrobiologisk ekspedisjon på 27010. Prøvebehandling Prøvemateriale
  3. Rhinoviruses (RVs) and respiratory enteroviruses (EVs) are leading causes of upper respiratory tract infections and among the most frequent infectious agents in humans worldwide. Both are classified in the Enterovirus genus within the Picornaviridae family and they have been assigned to seven distin
  4. Enteroviruses are a group of viruses that cause a number of infectious illnesses which are usually mild. However if they infect the central nervous system, they can cause serious illness. The two most common ones are echovirus and coxsackievirus, but there are several others. Enteroviruses also cause polio and hand, foot and mouth disease (HFMD), which are the subjects of separate factsheets
  5. Enterovirus Infection The symptoms & signs. Symptoms and Signs of an Enterovirus Infection. Although millions of people are infected annually with an enterovirus, most have only mild symptoms of the infection that only lasts about a week and resolves with no chronic problems

Enterovirus er vanligste årsak til serøs meningitt, og denne undersøkelsen bør derfor være med i standardrepertoaret ved slik sykdom. Undersøkelsen gir hovedsakelig prognostisk informasjon. Tidlig diagnostisering av enterovirusmeningitt bidrar dessuten til økonomiske besparelser ved at liggetid i sykehus forkortes Enterovirus 71 and viral meningitis (infection of the lining of the brain and/or spinal cord) and other neurological disease, such as viral encephalitis (infection of the brain), muscle weakness or paralysis Enterovirus D68 and severe respiratory illnesses in children and teenagers. This caused a nationwide outbreak in 2014 in the United States Hva er enterovirus: symptomer, årsaker, diagnose og behandling. Gjennom denne uken har vi lært at i øyeblikket er totalt 48 barn rammet i Catalonia (Spania) av enterovirus, hvorav 21 fortsetter å bli innlagt på sykehus (to av dem i intensivavdelingen som følge av følgesvikt og selve infeksjonen), som har begynt å varsle alle spanske barneleger Enterovirus infeksjon refererer til en gruppesykdommer som er forårsaket av intestinal virus - enterovirus. For øyeblikket er det mer enn 60 arter av patogener av enterovirus infeksjon. Faren for denne sykdommen ligger i det faktum at infeksjonen har en sterk motstandsdyktighet mot miljøeffekter Do you have photos and videos you need to share? Email us to upload a photo

Herpangina is caused by Coxsackie group A, Coxsackie B, enterovirus 71, and echovirus. Lesions develop on the mucous membranes, most often on the anterior tonsils, uvula, and soft palate of the mouth. Lesions are characterised by tiny grey-white papulovesicles about 1-2 mm in diameter. They are self-limiting and resolve over 5-10 days Non-cytolytic enterovirus is an aberrant form of enterovirus able to cause chronic infection.Normally enteroviruses only produce acute infections, but mutations to the virus acquired in the host can convert enterovirus B serotypes such as coxsackievirus B and echovirus into non-cytolytic viruses able to create persistent intracellular viral RNA infections Enterovirus RNA was detected in myocardial tissue from only a small proportion of (five of 75) hearts. 1177-1485. EVU6. SCDGGDTGGTGGTGGAA. 1177-1190. EVD6. YACYCCCATRCCRGCATT. 1485-1467 Detection of porcine teschovirus and enterovirus type II by reverse transcription-polymerase chain reaction Joseph M. Palmquist, Shirin Munir, Anil Taku, Vivek Kapur, Sagar M. Goyal Veterinary Population Medicin Enterovirus-Human Rhinovirus: A Rare Cause of Acute Respiratory Distress Syndrome Parita Soni, Anand Rai, Nidhi Aggarwal, Stephan Kamholz, Taek Yoon, Yizhak Kupfer. Journal of Investigative Medicine High Impact Case Reports, July 2017, SAGE Publications; DOI: 10.1177/232470961772852

Enterovirus Genotyping Tool Version 0.1 This tool is designed to use phylogenetic methods in order to identify the enterovirus genotype of a nucleotide sequence. Note for batch analysis: The genotypetool accepts up to 20000 sequences at a time 10.1177/104063870201400605. Link to publication in Scopus. Link to citation list in Scopus. Fingerprint Dive into the research topics of 'Detection of porcine teschovirus and enterovirus type II by reverse transcription-polymerase chain reaction' DOI: 10.1177/1352458520923978 Corpus ID: 220059103. Fatal underhanded chronic enterovirus infection associated with anti-CD20 monotherapy for central nervous system demyelinating disease Backgrounds HY12 viruses are enteroviruses recently isolated from cattle characterized by severe respiratory and digestive disease with high morbidity and mortality in China. While the viruses exhibit unique biological and molecular characters distinct from known enterovirus E, the pathogenicity and viral pathogenesis remains largely unknown. Methods Neonatal mice of Balb/C, ICR, and Kunming.

Guidance on discharge. When deciding on criteria for discharge of COVID-19 patients from hospital and ending home isolation of COVID-19 cases, health authorities should take into account the existing capacity of the healthcare system, laboratory diagnostic resources and the current epidemiological situation Enterovirus Genotyping Tool Methods. The (sero)typing process consists of up to two steps: The initial step performs an nucleotide blast scan, using Blastn.The submitted sequence is blasted against a set of whole genome sequences for determination of the genus within the Picornaviridae family and the species for enterovirus (enterovirus A, B, C, and D and rhinovirus A, B and C) The most common symptoms due to enterovirus D68 infection Symptoms reported in 195 children in 19 papers with individual data available. 1,6,8,9,11,15,20-22,24,25,35,36,40,43,45,47,50 Respiratory. Abstract. Dystrophic myocardial calcification occurs in the setting of myocardial injury and normal serum calcium. We present a case of a neonate with prominent dystrophic calcification and severe left ventricular systolic dysfunction in the setting of enterovirus myocarditis Enterovirus 71 (EV71) is a global infectious disease that affects millions of people. The virus is the main etiological agent for hand, foot, and mouth disease with outbreaks and epidemics being reported globally. Infection can cause severe neurological, cardiac, and respiratory problems in children under the age of 5. Despite on-going efforts, little is known about the pathogenesis of EV71.

Parvoviridae is a family of small, rugged, genetically-compact DNA viruses, known collectively as parvoviruses. There are currently more than 100 species in the family, divided among 23 genera in three subfamilies. Parvoviridae is the sole taxon in the order Quintoviricetes.. Parvovirus B19 was the first pathogenic human parvovirus to be discovered and is best known for causing a childhood. 1. Introduction. Hand, foot and mouth disease (HFMD) is an emerging life-threatening viral disease in young children, however, when the pathogen is Enterovirus 71 (EV71), the case can present with serious neurological symptoms and may even lead to death (Chang et al., 1999).Since the EV71 infection first broke out in California in 1969, more and more cases of EV71 infection subsequently have. and Enterovirus. Protozoans included are Cryptosporidium, Giardia, Dientamoeba fragilis, Entamoeba histolytica and Blastocystis hominis. BENEFITS OF TESTING • Improved detection of the targeted pathogens in the assay. • Improved detection of Dientamoeba fragilis when compared to conventional testing She was found to have enterovirus positive nasopharyngeal secretions by RT-PCR later confirmed as EV-D68. The results of her spirometry and LCI are shown in the Table. 4. Discussion. To our knowledge, this is the first report of EV-D68 infection and LCI in patients with CF before and after treatment for pulmonary exacerbation

Enterovirus D68 (EV-D68) was first isolated from children with pneumonia in 1962, but an association with AFM was not observed until the 2014 outbreak. Organotypic mouse brain slice cultures generated from postnatal day 1 to 10 mice and adult ifnar knockout mice were used to determine if neurotropism of EV-D68 is shared among virus isolates <jats:p>We amplified and sequenced the complete genome of enterovirus D68 (EV-D68) that had been collected from classroom air using a filter-based air samplin

enterovirus - Store medisinske leksiko

  1. Acute cerebellitis and acute cerebellar ataxia represent a spectrum of inflammatory processes characterized by sudden onset cerebellar dysfunction.It usually affects children and is related as a consequence of primary or secondary infection, or much less commonly as a result of a post-vaccination reaction
  2. Alison Christy, Kevin Messacar, Acute Flaccid Myelitis Associated With Enterovirus D68: A Review, Journal of Child Neurology, 10.1177/0883073819838376, (088307381983837), (2019). Crossre
  3. The pathogenesis and virulence of Bovine enterovirus-1 (BEV-1) in cattle is largely unknown. Reports concerning its virulence suggest that there might be an association between BEV-1 infections and a range of diseases in cattle that vary from respiratory to enteric to reproductive disease and infertility
  4. Autism Spectrum Disorder Secondary to Enterovirus Encephalitis: Autor: Marques, F Brito, MJ Conde, M Pinto, M Moreira, A: Palavras-chave: Brain/pathology Brain/radionuclide imaging Child Development Disorders, Pervasive/etiology Encephalitis, Viral/complications Encephalitis, Viral/etiology Enterovirus Infections/complications Magnetic.
  5. Enterovirus D68 (EV-D68) has historically been associated with respiratory illnesses. However, in the summers of 2014 and 2016, EV-D68 outbreaks coincided with a spike in polio-like acute flaccid myelitis/paralysis (AFM/AFP) cases. This raised concerns that EV-D68 could be the causative agent of AFM during these recent outbreaks. To assess the potential neurotropism of EV-D68, we utilized the.
  6. Patient education: Enterovirus D68 (The Basics) Beyond the Basics — Beyond the Basics patient education pieces are longer, more sophisticated, and more detailed. These articles are best for patients who want in-depth information and are comfortable with some medical jargon. Patient education: The common cold in adults (Beyond the Basics

Parvovirus B19 is a virus that infects humans only. Infection with the virus can cause different signs and symptoms, depending on the infected person's age and overall health Enterovirus 71 has been associated with encephalitis, while Rhinoviruses are a major cause of asthma exacerbations and chronic obstructive pulmonary disease. Based on the structure of both pleconaril and pirodavir, we previously synthesized some original compounds as potential inhibitors of Rhinovirus replication. \ud Methods

What Is Enterovirus? - Signs, Symptoms, Treatments

Enterovirus - Wikipedi

We amplified and sequenced the complete genome of enterovirus D68 (EV-D68) that had been collected from classroom air using a filter-based air sampling method and by swab sampling of environmental surfaces. Relatively high levels of EV-D68 genome equivalents were found per cubic meter of air by quantitative real-time reverse transcription-PCR (RT-PCR) Objectives This study aimed to prospectively collect detailed clinical information for all enterovirus (EV) and human parechovirus (HPeV) meningitis cases in infants aged <90 days in the UK and Ireland. Participants, design and setting Prospective, active national surveillance during July 2014 to July 2015 through the British Paediatric Surveillance Unit

Enterovirus - Universitetssykhuset Nord-Norge labhåndbo

Enterovirus 71 Infection-Associated Acute Flaccid Paralysis: A Case Series of Long-Term Neurologic Follow-Up Hsiu-Fen Lee, MD1,2, and Ching-Shiang Chi, MD2,3 Abstract The authors undertook long-term neurologic outcomes of 27 patients aged 0 to 15 years with enterovirus 71-related acute flac-cid paralysis from June 1998 to July 2012 This report describes, for the first time, a child with Miller-Fisher syndrome and documented Enterovirus infection, as it was proven by the isolation of Enterovirus from cerebrospinal fluid by polymerase chain reaction testing Searchable database of Enterovirus genomes with visualization and analysis tools Neonatal cardiogenic shock most commonly occurs due to critical congenital heart disease, sepsis, metabolic disorder or arrhythmias. In particular, enterovirus infections are common in the neonatal period, and patients can present with fulminant myocarditis. Early recognition is imperative due to its high morbidity and mortality without prompt and aggressive treatment

Order: unassigned: Family: Picornaviridae: Genus: Enterovirus: Accession: AB204853: Nucleic acid: ssRNA positive-strand viruses, no DNA stage: Targeted by: hsa-miR-432 Millions of children are infected by enteroviruses each year, usually exhibiting only mild symptoms. Nevertheless, these viruses are also associated with severe and life-threatening infections, such as meningitis and encephalitis. We describe a 32-month-old patient with enteroviral encephalitis confirmed by polymerase chain reaction in cerebrospinal fluid, with unfavorable clinical course with. A cytopathic virus was isolated using Madin-Darby bovine kidney (MDBK) cells from lung tissue of alpaca that died of a severe respiratory infection. To identify the virus, the infected cell culture supernatant was enriched for virus particles and a generic, PCR-based method was used to amplify potential viral sequences. Genomic sequence data of the alpaca isolate was obtained and compared with.

• Enterovirus studies during time of high prevalence or in patients with CSF pleocytosis • HSV in infants with clinical findings or increased risk of maternal HSV transmission CSF for viral culture if there is pleocytosis; if there is a limited CSF sample, we prioritize PCR over viral culture An official journal of the European Society of Cardiology. Publishes high quality material, both clinical and scientific, on all aspects of Cardiovascular Medi Autism Spectrum Disorder Secondary to Enterovirus Encephalitis: Author: Marques, F Brito, MJ Conde, M Pinto, M Moreira, A: Keywords: Brain/pathology Brain/radionuclide imaging Child Development Disorders, Pervasive/etiology Encephalitis, Viral/complications Encephalitis, Viral/etiology Enterovirus Infections/complications Magnetic Resonance Imagin other enterovirus equine antisera is nowinprogress. A collaborative study made by a number of WHO Regional Reference Centres, WHO Virus Collaborating Laboratories and a numberof other * From the WHO International Reference Centre for Enteroviruses, Department of Virology and Epidemiology, Baylor University College ofMedicine, Houston,Tex., USA

Enterovirus Detection (Real-Time Pcr) Institute of Pathology. St. Luke's Medical Center - Global City. 2nd Floor, Institute of Pathology, Main Building. 8-789-7700 ext. 2062. St. Luke's Medical Center - Quezon City. 1st Floor, Main Hospital. 8-723-0101 ext. 5423. LOCATIONS A series of novel pyrazolopyridine compounds have been designed and prepared by a general synthetic route. Their activities against the replication of poliovirus-1, EV-A71, and CV-B3 enteroviruses were evaluated. The comprehensive understanding of the structure-activity relationship was obtained by utilizing the variation of four positions, namely, N1, C6, C4, and linker unit. From the.

Rhinoviruses and Respiratory Enteroviruses: Not as Simple

Salmonella, Campylobacter och Enterovirus finns i vanligtvis låga halter i avloppsvatten. Mikroorganismer i reningsverk På VA-verk kan man utsättas för mikroorganismer som bakterier, virus och parasiter. Mikroorganismerna förekommer i hela reningsprocessen och i slammet. Arbetsmiljöproblem uppstår vid We have determined the crystal structure of a bovine enterovirus, revealing that the topologies of the major capsid proteins and the overall architecture of the virion are similar to those of. Main content area. Efficient replication of recombinant Enterovirus B types, carrying different P1 genes in the coxsackievirus B5 replicative backbon

Factsheet about enteroviruse

enterovirus 5'ntr 63-377 evd3 caggccgccaacg 375-363 evu3 cggtacctttgtgcgcctgt 63-82 evd4 ggcaggccgccaacg 377-363 evu5 ccccggactgagtatc 180-195 evd5 agtgctgagcgaaacac 299-283 enterovirusvp2 1177-1485 evu6 scdggdtggtggtggaa 1177-1190 evd6 yacycccatrccrgcatt 1485-1467 evu7 tggrcaraayatgcartaycactac 1225-124 Enterovirus D68 (EV-D68) was detected in 93 patients from five European countries between 1 January 2019 and 15 January 2020, a season with expected low circulation. Patients were primarily children (n = 67, median age: 4 years), 59 patients required hospitalisation and five had severe neurologic manifestations. Phylogenetic analysis revealed two clusters in the B3 subclade and subclade A2/D Bull. Org. mond. Sante 1970, 42, 847863 Bull. WidHith Org. WHOCollaborative Studies onEnterovirus Reference Antisera* Third Report JOSEPH L. MELNICK&BETIYLEE HAMPIL OnBehalfofthe Participating LaboratoriesI Thispapersummarizes the results ofthe thirdpart ofco-operative studies undertaken by the WHOInternational Reference Centrefor Enteroviruses anda number of WHO. Haemophilus influenzae disease is a name for any illness caused by bacteria called H. influenzae.Some of these illnesses, like ear infections, are mild while others, like bloodstream infections, are very serious. In spite of the name, H. influenzae do not cause influenza (the flu).Vaccines can prevent one type of H. influenzae (type b or Hib) disease

Symptoms & Signs — Enterovirus Foundatio

Enteroviruses belong to the Picornaviridae family and are small icosahedral viruses with RNA genomes of positive polarity, containing a single open reading frame. They mostly cause mild or asymptom. Download and reference Enterovirus 71 Suppresses MiR-17-92 Cluster Through Up-Regulating Methylation Of The MiRNA Promoter by Yuxuan Fu, L. Zhang, R. Zhang, S. Xu, Huanru Wang, Yu Jin, Zhiwei Wu on Citations Zika virus is an emerging mosquito-borne virus that was first identified in Uganda in 1947 in rhesus monkeys through a monitoring network of sylvatic yellow fever

Enterovirusinfeksjoner diagnostisert i Midt-Norge i

Felleskatalogen (1177) Folkehelseinstituttet (753) Frambu (10) Helsebiblioteket (2102) Legemiddelhåndboken (110) Metodebok for sykehjemsleger (3) Relis (1129) Store Medisinske Leksikon (53) Tidsskrift for Den norske legeforening (715) Informasjonstype. Oppslagsverk (110) Legemidler (110) Språk. Norsk (110 Cerebrospinal fluid (CSF) was negative for Japanese B encephalitis, enterovirus, herpes simplex 1 and 2, varicella and mumps viruses as determined by real-time polymerase chain reaction (PCR). P. falciparum and P. vivax species were analysed by microscopy, immunochromatography and PCR assays and confirmed mono-infection of P. vivax in the patient's blood, and P. falciparum infection was.

Enterovirus detection in cattle and goat feces. Real-time reverse transcription-PCR (RT-PCR) of the 5′ UTR was used to detect the presence of EVs in fecal samples collected from various areas in Kanchanaburi Province ().As shown in Table 1, 62 of 157 cattle samples (39.5%) and 55 of 117 goat samples (47%) tested positive for EV infection.Details of the virus detection on each farm are. Skip to Main Content (Press Enter) Sign in | Register | MobileMobile

Enteroviruses fact sheet - Fact sheet

The homogeneity of 8 CA16 strains shared 89.9%-100.0% in nucleotide acid identity and 99.3%-100.0% in amino acid identity,6 strains belonged to CA16 B1b subgenotype and 2 belonged to CA16 B1a subgenotype. Conclusion C4a subgenotype of EV71,B1b and B1a subgenotype of CA16 were the major pathogens for the epidemics of HFMD in Dongguan in 2014,while there was also other enterovirus co-existed Biotinylated complementary DNA (cDNA) and RNA probes were prepared from a specific and highly conserved section of the foot-and-mouth disease virus (FMDV) genome coding for the RNA-dependent RNA polymerase. Hybridization was conducted on FMDV-infected, bovine enterovirus (BEV)-infected, and noninfected swine kidney cell cultures Enterovirus. Enterovirus D68 (EV-D68) Flu Season. Hand-Foot-Mouth Disease. Mouth Blisters (Herpangina) Pink Eye. Strep Throat. Upper Respiratory Infection. Vomiting and Diarrhea. Whooping Cough (Pertussis Echovirus Infections Echovirus 9 Echovirus 6, Human Enterovirus B, Human Meningitis, Aseptic Enterovirus Enterovirus Infections Meningitis, Viral Antigens, CD55 Poliovirus Receptors, Virus Disease Outbreaks Cerebrospinal Fluid Picornaviridae Sewage Orphanages Skin Manifestations Coxsackievirus Infections Capsid Integrin alpha2beta1 RNA, Viral Hemagglutination, Viral Glutaral Haplorhini. Camilla Buoen, Ole J. Bjerrum, Mikael S. Thomsen, How First‐Time‐in‐Human Studies Are Being Performed: A Survey of Phase I Dose‐Escalation Trials in Healthy Volunteers Published Between 1995 and 2004, The Journal of Clinical Pharmacology, 10.1177/0091270005279943, 45, 10, (1123-1136), (2013)

Hva er enterovirus: symptomer, årsaker, diagnose og

Information sammanställd av barnmorska Marie Sjödin. Reviderad 2019 av barnmorska Helene Bernmark-Liikamaa Faktagranskad av Överläkare Karin Petersson, INFPRE Nausea and vomiting are very common symptoms in the paediatric population. Whether presenting in the emergency department or in an outpatient clinic, they are a frequent reason for parents and caregivers to seek medical attention. As a result, they have a significant impact on healthcare costs Mazelen (morbilli) is een ziekte die veroorzaakt wordt door het mazelenvirus en vooral kinderen treft. Het mazelenvirus behoort tot de virusfamilie paramyxoviridae, genus morbilli.Het is een enkelstrengs RNA-virus. Hoewel er een veilig en goedkoop vaccin beschikbaar is, is mazelen een van de belangrijkste oorzaken van kindersterfte wereldwijd Download and reference Enterovirus 71 Uses Cell Surface Heparan Sulfate Glycosaminoglycan As An Attachment Receptor by C. W. Tan, C. L. Poh, I. Sam, Y. Chan on Citations

diarrhoea DEF

enterovirus infeksjo

Behandling av Pneumoni (Sjukhus) Samhällsförvärvad pneumoni (SFP) Empirisk behandling: bensylpenicillin (penicillin G) 5 mill IE (3 g) x 4 IV Akut Pc-allergi: erytromycin 500 mg x 4 PO eller IV: Mycoplasma/Chlamydiapneumoni: erytromycin 500 mg x 4 PO, alternativt IV i 10-14 dagar Alternativ: doxycyklin 100 mg x 2 IV, alternativt PO dag 1-3, därefter 100 mg x Analysworkshop 8 maj 2019: Varför ser det ut som det gör? Konferens 5 oktober 2018: Ekonomiska effekter av sociala insatser. Konferens april 2018: Agenda 203 Gitta Turowski. MD, PhD +47 22 11 89 48 . Publications 2018. Feist H, Turowski G, Hussein K, Blöcker T, Heim A (2018) Massive Perivillous Fibrin Deposition of an Enterovirus A-Infected Placenta Associated With Stillbirth: A Case Report Pediatr Dev Pathol, 22 (2), 142-145 DOI 10.1177/1093526618798772, PubMed 30193561. Froehlich K, Stensheim H, Markert UR, Turowski G (2018) Breast carcinoma in. Informationen sammanställd av barnmorska Marie Sjödin 2006. Reviderad av Barnmorska Cecilia Brolinger/INFPREG Faktagranskad av Docent Stellan Håkansson och Med. dr Bo Jacobsson 2006 samt av Med. dr Karin Petersson 2009 samt 201 The mitogen-activated protein kinase kinase/extracellular-signal-regulated kinase (MEK/ERK) signaling pathway is involved in viral life cycle. However, the effect of MEK/ERK pathway in enterovirus 71(EV71)-infected immature dendritic cells (iDCs) is still unclear. Human peripheral blood mononuclear cells (PBMCs) were isolated and induced to generate iDCs

People with Down syndrome have an extra chromosome that impacts how a person looks and their ability to think, learn, and reason. Find out the type, causes, and kinds of effects it can have Meningitis is inflammation of the fluid that surrounds the brain and spinal cord. It is typically caused by a viral (most common) or bacterial infection, the latter of which is significantly more serious and can be fatal if untreated

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